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What is alopecia areata?

A common skin condition, alopecia areata usually starts as a single quarter-sized circle of perfectly smooth bald skin. These patches usually regrow in three to six months without treatment. Sometimes, white hair temporarily regrows and then becomes dark. The most extensive form is alopecia totalis, in which the entire scalp goes bald. It’s important to emphasize that patients who have localized hair loss generally don’t go on to lose hair all over the scalp. Alopecia areata can affect hair on other parts of the body, too (for example, the beard or eyebrows).

Alopecia areata is an autoimmune condition in which the body attacks its own hair follicles. Most patients, however, do not have systemic problems and need no medical tests. While people frequently blame alopecia areata on “stress,” in fact, it may be the other way around; that is, having alopecia may cause stress.

Treatments for alopecia areata include injecting small amounts of steroids like triamcinolone into affected patches to stimulate hair growth. Although localized injections may not be practical for large areas, often this is a very effective treatment in helping the hairs return sooner. Other treatments, such as oral steroids, other immunosuppressives, or ultraviolet light therapy, are available for more widespread or severe cases but may be impractical for most patients because of potential side effects or risks. In most mild cases, patients can easily cover up or comb over the affected areas. In more severe and chronic cases, some patients wear hairpieces; nowadays, some men shave their whole scalp now that this look has become fashionable. Recently, investigators have noted some beneficial results in small groups of patients with extensive alopecia areata or alopecia totalis with a JAK1/2 inhibitor, baricitinib (Olumiant). Long-term studies are under way.

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